Sitemap - 2024 - Decoding Bio

BioByte 101: de novo antibody design, measuring how fast your brain is aging, enhancing GWAS, commentary on trial results, and more

BioByte 100: integrating biological complexity into AI, scaling connectomics to the human brain, deep brain stimulation for spinal cord injury, ESM Cambrian launch

BioByte 099: Ferroptosis across disease, adipose retains epigenetic memory, Cephalopod-inspired drug delivery, and predicting RNA 3D structures

BioByte 098: big challenges in protein-design, OpenAI takes clinical trials, how non-neural cells remember and predicting psychiatric disease from social media.

BioByte 097: Drivers of biological progress, immunogenicity in gene therapy & a vision for AI scientists

BioByte 096: brain shuttles for antibody delivery, immune privilege in the brain, DNA data storage, clinical translation of spatial biology

BioByte 095: Using autrotrophs for food production, the future of computational drug discovery, calls for a CRISPR revolution, a proteogenomic pipeline for neoantigen discovery

BioByte 094: industry consortium for benchmarking, evaluating protein competitions, multimodal atlas for Alzheimer's, automated organelle tracking, promise of a new HAE treatment

BioByte 093: A big week for AI, GLP-1s program the neurovascular landscape , an AAV primer and LLCs in biotech

BioByte 092: reversing diabetes with cell therapy, the effect of mislocalization of proteins within a cell, DNA methylation in the brain, NIH-wide exposome research centre launch

BioByte 091: quantum biology, a foundation model for drug repurposing, functional genomic variant interpretation, and new mechanisms in brain metabolism

BioByte 090: LLMs for novel research, the chemistry synthesis bottleneck, on the origin of viruses, molecular de-extinction, and targeted protein relocalization

BioByte 089: ten commandments of drug R&D, a foundation model for CGMs, expanding the genetic code without modifying the genome

It's our second birthday. Help us improve!

BioByte 088: AlphaProteo, Merck's Blockbuster Recipe, Dark Genome and Grand Challenges in Healthcare

BioByte 087: Push for biodiversity data, Recursion's Big Moment, Conditional Generation of Molecules, Graph AI Applied, Evolved Hackathon, and more

BioByte 086: Recursion and Exscientia join forces, music as a brain-computer interface, microglial rescue patterns in neurodegenerative disease, and ribonucleoprotein granules and protein synthesis

BioByte 085: monte carlo models in drug discovery, we don't know how antidepressants work, single cell atlas for Alzheimer's Disease, extending lifespan with IL-11, impact of diet on the microbiome

BioByte 084: A history of Regeneron, 3D genome preserved in wooly mammoth skin, assessing LLMs for biology, technology to overcome the cold chain

BioByte 083: neurolipid atlas in neurodegenerative disease, the role of iron in large-scale cell death, Benchling and Flagship CEOs on AI

BioByte 082: a novel gene editing paradigm, drug factories and advice for life

BioByte 081: AF3 docking accuracy, reflections on top 50 biotechs, brain data lawsuit, "cervix-on-a-chip", ethics x life sci collabs

BioByte 080: "Bust to Boom" in biotech, gene editing in the lungs, advancements in colonic organoids, increasing access to pediatric CGT

BioByte 079: advances in brain delivery of gene therapies, RNA delivery heats up cold tumours, AF3 guide, polyextremophile engineering launch, and an LLM for therapeutics

BioByte 078: a foundation model for life's chemistry, reprogramming the germ line and AI losing steam

Decoding Bio Snapshot 2024

Decoding Bio is evolving. Come check it out!

BioByte 077: Body axis maps, efficiency of pharma R&D, focused research organizations in atomistic simulation, GLP-1 directed NMDA antagonism

BioByte 076: AlphaFold3, engineering antibody agonists, NfL as a biomarker for neuro disease, diffusion models for molecular linker design

BioByte 075: Next generation antibodies, CRISPR beyond the liver, 85 Million cells at your fingertips

BioByte 074: Why Mars is tough for life, an autoantibody signature for MS, selective compartmentalization for proteins, AI-designed CRISPR, RNAi-based drug design

BioByte 073: citizen science for DNA sequence alignment, cellular niches, updates in AI antibody design, polarizing biotech investment trends

BioByte 072: DNA printing, edible neuromodulatory electronics, AI agents empower biomedical discovery, scRNAseq supports successful drug targets, $100M seed round for gene editing delivery newco

BioByte 071: Unanswered questions, paused base-editing therapy, challenges with ASOs, GPT-4 for cell type annotation, the scientific journey behind Ozempic

BioByte 070: NeuroAI, proteome-scale screening of protein degraders, open source biomedical LLMs, engineering better mRNA therapeutics

BioByte 069: AI learns the meaning of life, the dysfunctome, a $400M launch for inflammatory drugs, Nvidia's 'woodstock' and engineering crops to save the planet

BioByte 068: Cell therapy for solid tumors, using a monoclonal for allergy, improving AlphaFold2 performance, using ML to understand small RNA secretion, Insilico's development of a TNIK inhibitor

BioByte 067: DNA foundation models, neural multi-task learning for drug design, non-invasive methods for brain amyloid clearance, clinical trial architectures for precision medicine

BioByte 066: CAR-T for MS, will AI replace animal testing, diagnosis of ultra-rare monogenic disorders, BigRNA: a foundation model for RNA biology, Matter Neuro raises $26M to “cure unhappiness"

BioByte 065: RNA-editing therapies pick up steam, experts speak on protein design, decoding the autoantibody reactome, links between menopause and healthy aging, and more

BioByte 064: LLMs for neuro, bias in protein language models, engineered T-cell therapeutics inspired by T-cell cancers, AI for molecular glues

BioByte 063: How to develop a blockbuster, unravelling the biology of autoimmunity, partnering with pharma and a new model for intrinsically disordered proteins.

BioByte 062: First RNA-editing trial in US, an integrated classification of Parkinson's, shortening CAR-T manufacturing, cell surface RNAs control neutrophil recruitment

Scaling Biology 002: Gevorg Grigoryan, Co-Founder and CTO at Generate:Biomedicines

BioByte 061: AI for Alzheimer's prediction, NeurIPS 2023 recap, gene therapy for hearing loss, autonomous chemical discovery, and 3D molecular generation

BioByte 060: astrocyte plasticity, a foundation model for RNA structure, improved confidence in biotech activity in '24, predicting therapeutic perturbations, isomorphic's deals